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Found 6 Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-9' and Ligand = 'BDBM50264811'
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)
Affinity DataKi:  130nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)
Affinity DataKi:  130nMAssay Description:Inhibition of human recombinant MMP9 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)
Affinity DataKi:  130nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)
Affinity DataKi:  3.40E+3nMAssay Description:Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)
Affinity DataKi:  3.40E+4nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50264811(CHEMBL485492 | N-(4-(4-(thiiran-2-ylmethylsulfonyl...)
Affinity DataIC50:  529nMAssay Description:Inhibition of human full length MMP9 using Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 2 hrs prior to testing measured for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed