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Found 6 Enz. Inhib. hit(s) with Target = 'Matrix protein 2' and Ligand = 'BDBM50216627'
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National And Kapodistrian University Of Athens

Curated by ChEMBL
LigandPNGBDBM50216627((alpha-methyl-1-adamantyl)methylamine | 1-Adamanta...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes assessed as blockade of inward currents at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National And Kapodistrian University Of Athens

Curated by ChEMBL
LigandPNGBDBM50216627((alpha-methyl-1-adamantyl)methylamine | 1-Adamanta...)
Affinity DataKd:  7.00E+3nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)TBA
LigandPNGBDBM50216627((alpha-methyl-1-adamantyl)methylamine | 1-Adamanta...)
Affinity DataKd:  510nMAssay Description:Binding affinity to C-terminal amidated influenza A virus A/Udorn/72 (H3N2) M2 transmembrane domain (22 to 46 residues) in DPC micelles at pH 8 asses...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National And Kapodistrian University Of Athens

Curated by ChEMBL
LigandPNGBDBM50216627((alpha-methyl-1-adamantyl)methylamine | 1-Adamanta...)
Affinity DataKd:  510nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2(Influenza A virus)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50216627((alpha-methyl-1-adamantyl)methylamine | 1-Adamanta...)
Affinity DataKd:  16nMAssay Description:Binding affinity to Influenza A Weybridge(H7N7) virus Matrix protein 2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National And Kapodistrian University Of Athens

Curated by ChEMBL
LigandPNGBDBM50216627((alpha-methyl-1-adamantyl)methylamine | 1-Adamanta...)
Affinity DataKd: >1.00E+7nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 M2 proton channel S31N mutant expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed