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Found 12 Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 3' and Ligand = 'BDBM82411'
TargetMelanocortin receptor 3(Homo sapiens (Human))
Uppsala

Curated by PDSP Ki Database
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataKi:  0.224nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Uppsala

Curated by PDSP Ki Database
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataKi:  0.680nMAssay Description:Binding affinity towards human Melanocortin 3 receptor (hMC3R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Uppsala

Curated by PDSP Ki Database
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory concentration against human Melanocortin 3 receptor (hMC3R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Uppsala

Curated by PDSP Ki Database
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [125I]NDP-MSH from Melanocortin 3 receptor at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Uppsala

Curated by PDSP Ki Database
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Uppsala

Curated by PDSP Ki Database
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataIC50:  3.80nMAssay Description:Inhibitory activity against Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Mus musculus)
University Of Florida

Curated by ChEMBL
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  75nMAssay Description:Compound was evaluated for its agonist activity on mouse melanocortin receptor 3 (mMC3R) stably expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Uppsala

Curated by PDSP Ki Database
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  4.10nMAssay Description:Effective concentration that was able to generate 50% maximal intracellular cAMP in L-cells transfected with Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Uppsala

Curated by PDSP Ki Database
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  0.800nMAssay Description:Effective concentration of peptide at 50% maximal cAMP generationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Uppsala

Curated by PDSP Ki Database
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  4.10nMAssay Description:effective concentration of peptide at 50% maximal cAMP accumulation on Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Uppsala

Curated by PDSP Ki Database
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  0.132nMAssay Description:Evaluated for agonist activity at cloned Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Uppsala

Curated by PDSP Ki Database
LigandPNGBDBM82411(CAS_75921-69-6 | NDP-MSH)
Affinity DataEC50:  0.360nMAssay Description:In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed