Found 34 Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50121900' 
Affinity DataKi: 0.560nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R F184L expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y268F expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R I291A expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R I129A expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R F184A expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.820nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human wild type MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.970nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y287F expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R I125A expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y268A expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Displacement of [125I]NDP-alpha-MSH from mutant MC4R Y287A expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Displacement of Eu-NDP-alphaMSH from human MC4 receptor expressed in human HEK293 cells after 1.5 hrs by time-resolved fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.22nMAssay Description:Inhibitory concentration towards melanocortin MC4 receptor by displacing radioligand [125I]-NDP-MSH; ND = not determinedMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonist activity at the mutant MC4R Y268A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at the mutant MC4R Y268F expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 5.10nMAssay Description:Agonist activity at the mutant MC4R I291A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at the mutant MC4R I129A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.510nMAssay Description:Agonist activity at the mutant MC4R F184A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.130nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells by beta-galactosidase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Agonist activity at mouse MC4 receptor expressed in HEK293 cells after 6 hrs by cAMP-based beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.140nMAssay Description:Agonistic activity against mouse MC4RMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0970nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Agonist activity at the human wild type MC4R expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at the mutant MC4R F184L expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Agonist activity at the mutant MC4R Y287A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at the mutant MC4R Y287F expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at the mutant MC4R I125A expressed in HEK293 cells by cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.140nMAssay Description:In vitro agonist potency for Mouse Melanocortin 4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.160nMAssay Description:Effective concentration for mouse Melanocortin-4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.210nMAssay Description:Effective concentration against mouse melanocortin MC4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.210nMAssay Description:Agonist activity to the mouse Melanocortin-4 receptor (mMC4R)More data for this Ligand-Target Pair
Affinity DataEC50: 0.210nMAssay Description:Activity in mouse melanocortin-4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.210nMAssay Description:In vitro activaction of mouse recombinant Melanocortin-4 receptor.More data for this Ligand-Target Pair
Affinity DataEC50: 0.120nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells by CRE/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.320nMAssay Description:Functional activity at the mouse melanocortin 4 receptorMore data for this Ligand-Target Pair
