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Found 3 Enz. Inhib. hit(s) with Target = 'Membrane primary amine oxidase' and Ligand = 'BDBM220866'
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM220866(US11472769, Compound BI-1467335-(PXS-4728A) | US93...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant VAP-1 using benzylamine as substrate incubated for 30 mins followed by substrate addition measured every 2.5 mins for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM220866(US11472769, Compound BI-1467335-(PXS-4728A) | US93...)
Affinity DataIC50: <1.00E+5nMpH: 7.4Assay Description:Briefly, HMEC cell expressing human SSAO/VAP-1 were grown in several 10 cm petri dishes, once the cells reached 100% confluency, cells were harvested...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMembrane primary amine oxidase(Rattus norvegicus (Rat))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM220866(US11472769, Compound BI-1467335-(PXS-4728A) | US93...)
Affinity DataIC50: <1.00E+5nMpH: 7.4Assay Description:Abdominal fat from BALB/c mice, Wistar or Sprague Dawley rats, which are tissues enriched with SSAO/VAP-1-were surgically removed. For every gram of ...More data for this Ligand-Target Pair
In DepthDetails US Patent