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Found 3 Enz. Inhib. hit(s) with Target = 'Menin' and Ligand = 'BDBM50516553'
TargetMenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50516553(CHEMBL4476073 | US10899738, Cpd. No 151)
Affinity DataKi:  4.60nMAssay Description:Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50516553(CHEMBL4476073 | US10899738, Cpd. No 151)
Affinity DataIC50:  15nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50516553(CHEMBL4476073 | US10899738, Cpd. No 151)
Affinity DataIC50:  17nMAssay Description:Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed