Found 6 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 3' and Ligand = 'BDBM50094841'
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 65.9nMAssay Description:Tested for binding affinity against Metabotropic glutamate receptor 3 in CHO cells using [3H]-7 as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human mGlu3 receptor expressed in CHO cell membranes in presence of glutamate by GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: 45.4nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
Affinity DataEC50: 76nMAssay Description:Agonist activity at human mGlu3 receptor expressed in CHO cell membranes by GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: 97nMAssay Description:Agonist activity at rat mGlu3 receptor expressed in CHO cell membranes by GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Antagonist activity against Metabotropic glutamate receptor 3 expressed in CHO cells was evaluated in presence of 30 microM glutamic acidMore data for this Ligand-Target Pair