Found 4 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50181753' TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataKi: 0.710nMAssay Description:Displacement of [3H]MPEP from mGluR5 in rat brain membranesMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataKi: 1.00nMAssay Description:Displacement of [3H]MPEP from cloned human mGluR5 transfected in HEK293-T cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataKi: 1.40nM ΔG°: -50.5kJ/moleT: 2°CAssay Description:Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 2.01nMAssay Description:Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5aMore data for this Ligand-Target Pair
