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Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50337957'
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50337957((4-hydroxypiperidin-1-yl)(4-(phenylethynyl)phenyl)...)
Affinity DataEC50:  270nMAssay Description:Positive allosteric modulation of rat mGlu5 expressed in HEK293 cells in presence of glutamate EC20 concentration by Fluo-2AM dye based fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt Medical Center

Curated by ChEMBL
LigandPNGBDBM50337957((4-hydroxypiperidin-1-yl)(4-(phenylethynyl)phenyl)...)
Affinity DataEC50:  10nMAssay Description:Positive allosteric modulation of mGlu5 receptor assessed as calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed