Found 8 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50395923' 
Affinity DataIC50: 2.60nMAssay Description:Negative allosteric modulation of rat recombinant mGluR5 expressed in HEK293 cells expressing GLAST assessed as inhibition of DHPG-induced intracellu...More data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells expressing GLAST assessed as inhibition of DHPG-induced intracel...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells expressing GLAST assessed as inhibition of glutamate-stimulated ...More data for this Ligand-Target Pair
Affinity DataKd: 2.25nMAssay Description:Binding affinity to human mGluR5 expressed in HEK293 cell membranes expressing GLAST by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKd: 5.5nMAssay Description:Binding affinity to human mGluR5 expressed in HEK293 cell membranes expressing GLAST after 1 hr by scintillation counter in presence of 10 nM MPEPMore data for this Ligand-Target Pair
Affinity DataKd: 7.20nMAssay Description:Binding affinity to human mGluR5 expressed in HEK293 cell membranes expressing GLAST after 1 hr by scintillation counter in presence of 20 nM MPEPMore data for this Ligand-Target Pair
Affinity DataKd: 9.40nMAssay Description:Binding affinity to mGluR5 in Sprague-Dawley rat striatum after 60 mins by autoradiographic analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3.80nMAssay Description:Binding affinity to human mGluR5 expressed in HEK293 cell membranes expressing GLAST after 1 hr by scintillation counter in absence of MPEPMore data for this Ligand-Target Pair
