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Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM511433'
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM511433((-)-(1R,5S)-2-[5-(4-Fluoro-phenylethynyl)-pyridin-...)
Affinity DataKi:  4nMAssay Description:For binding experiments, cDNA encoding human mGlu5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM511433((-)-(1R,5S)-2-[5-(4-Fluoro-phenylethynyl)-pyridin-...)
Affinity DataEC50:  4nMAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent