Found 8 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 8' and Ligand = 'BDBM17657' TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Affinity DataKi: 3.40E+3nMAssay Description:Displacement of [3H]LY341495 from rat mGluR8 expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Affinity DataKi: 9.50E+3nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 8 (mGluR-8).More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Affinity DataIC50: 5.70nMAssay Description:Inhibitory concentration against [3H]1 binding to recombinant human Metabotropic glutamate receptor 8More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+4nMAssay Description:Agonist activity at rat mGlu8 receptor expressed in HEK293 cells assessed as IP1 accumulation by IP-One functional assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.00E+3nMAssay Description:Agonist activity in rat at Metabotropic glutamate receptor 8 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR8 in mouseMore data for this Ligand-Target Pair
