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Found 2 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 10/8/9' and Ligand = 'BDBM50506721'
TargetMitogen-activated protein kinase 10/8/9(Homo sapiens (Human))
Montana State University

Curated by ChEMBL
LigandPNGBDBM50506721(CHEMBL4582239)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of JNK in human THP1-Blue cells assessed as reduction in LPS-induced NFkappaB/AP1 activation preincubated for 30 mins followed by LPS-stim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10/8/9(Homo sapiens (Human))
Montana State University

Curated by ChEMBL
LigandPNGBDBM50506721(CHEMBL4582239)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of JNK in human MONO-MAC-6 cells assessed as reduction in LPS-induced IL6 production preincubated for 30 mins followed by LPS-stimulation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed