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Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 11/12/13/14' and Ligand = 'BDBM50130657'
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50130657(CHEMBL109331 | {4-[5-(4-Fluoro-phenyl)-2-methylsul...)
Affinity DataIC50:  41nMAssay Description:Inhibitory activity against induction of IL-1-beta release in PBMCsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50130657(CHEMBL109331 | {4-[5-(4-Fluoro-phenyl)-2-methylsul...)
Affinity DataIC50:  170nMAssay Description:Inhibitory activity against TNF-alpha release in PBM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50130657(CHEMBL109331 | {4-[5-(4-Fluoro-phenyl)-2-methylsul...)
Affinity DataIC50:  340nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 at 10 e-4 to 10 e-8 M concentrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed