Found 4 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 8' and Ligand = 'BDBM50392982'
Affinity DataIC50: 44nMAssay Description:Inhibition of JNK1 after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of human JNK1 alpha1 using GST-tagged ATF2 as substrate and [gamma33P]ATP incubated for 10 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
Affinity DataKd: 62nMAssay Description:Binding affinity to T7-phage-tagged JNK1 by PCR analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 1.01E+4nMAssay Description:Inhibition of JNK1-mediated c-jun phosphorylation in TNF-alpha stimulated human HK-2 cells after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair