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Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 10' and Ligand = 'BDBM24942'
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Califia Bio

Curated by ChEMBL
LigandPNGBDBM24942(CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...)
Affinity DataIC50:  2nMAssay Description:Inhibition of MLK2 (unknown origin) after 20 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Califia Bio

Curated by ChEMBL
LigandPNGBDBM24942(CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...)
Affinity DataIC50:  51nMAssay Description:Inhibition of recombinant GST-tagged full length human MLK2 KD/LZ expressed in baculovirus using myelin basic protein as substrate preincubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Califia Bio

Curated by ChEMBL
LigandPNGBDBM24942(CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...)
Affinity DataIC50:  51nMAssay Description:Inhibition of Mixed lineage kinase 2(MLK2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed