Found 12 Enz. Inhib. hit(s) with Target = 'Motilin receptor' and Ligand = 'BDBM50344942' TargetMotilin receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 3.70E+4nMAssay Description:In vitro binding affinity towards human motilin receptorMore data for this Ligand-Target Pair
3D Structure (crystal)TargetMotilin receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Compound was tested for in vitro motilin receptor binding affinityMore data for this Ligand-Target Pair
TargetMotilin receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 71nMpH: 2.5Assay Description:Compound was tested for in vitro motilin receptor binding affinity after treatment with hydrochloric acid solution (pH 2.5)More data for this Ligand-Target Pair
TargetMotilin receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at motilin receptorMore data for this Ligand-Target Pair
TargetMotilin receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 50.1nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
TargetMotilin receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 50.1nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
TargetMotilin receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 631nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as increase of muscle contractionMore data for this Ligand-Target Pair
TargetMotilin receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:In vitro effective concentration towards human motilin receptorMore data for this Ligand-Target Pair
TargetMotilin receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at motilin receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Agonist activity at motilin receptor in rabbit smooth muscle assessed as maximal possible tissue contractionMore data for this Ligand-Target Pair
