Found 65 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM50004656' 
Affinity DataKi: 700nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor F92C/F550C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 990nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor F92C/R551C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.04E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor F92C/T549C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.26E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor F92C/K548C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.22E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor K93C/F550C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.41E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor N95C/R551C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.59E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor N95C/F550C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.47E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor A91C/F550C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.60E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor N95C/T549C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.68E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor V94C/R551C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.95E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor A91C/K548C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.41E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor K93C/T549C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.52E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor N95C/K548C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.94E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor A91C/T549C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.25E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor K93C/R551C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.57E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor A91C/R551C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.82E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor V94C/F550C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.69E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor V94C/T549C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 9.14E+3nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor K93C/K548C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataKi: 1.38E+4nMAssay Description:Displacement of [3H]NMS from rat M3'(3C)-Xa receptor V94C/K548C mutant expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataKi: 2.00E+4nMAssay Description:Binding affinity of compound was determined towards human Muscarinic acetylcholine receptor M3 using [3H]-QNB radioligandMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataKi: 4.37E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO cells by microplate scintillation countingMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataKi: 4.37E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO cells by liquid scintillation counterMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataKi: 4.37E+4nMAssay Description:Displacement of [3H]NMS from human cloned muscarinic M3 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataKi: 4.37E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor transfected in CHO cells after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataKi: 4.37E+4nMAssay Description:Binding affinity to cloned human muscarinic M3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataKi: 5.10E+4nMAssay Description:Displacement of [3H]N-methyl-scopolamine bromide from human recombinant muscarinic M3 receptor expressed in HEK293T cell membranes after 1 hr by liqu...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataIC50: 880nMAssay Description:Compound was evaluated for its binding affinity at human muscarinic receptor m3 by the displacement of [3H]NMS radioligand using membranes from trans...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataIC50: 9.10E+3nMAssay Description:In vitro affinity of the compound is evaluated, using quinuclidynyl benzylate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.62E+5nMAssay Description:Inhibition of disulfide bond cross-linking formation in rat M3'(3C)-Xa receptor F92C/F550C mutant expressed in african green monkey COS7 cells by sca...More data for this Ligand-Target Pair
Affinity DataIC50: 8.18E+5nMAssay Description:Inhibition of disulfide bond cross-linking formation in rat M3'(3C)-Xa receptor A91C/T549C mutant expressed in african green monkey COS7 cells by sca...More data for this Ligand-Target Pair
Affinity DataEC50: 197nMAssay Description:Agonist activity at rat M3'(3C)-Xa receptor K93C/T549C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h...More data for this Ligand-Target Pair
Affinity DataEC50: 66nMAssay Description:Agonist activity at rat M3'(3C)-Xa receptor K93C/F550C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h...More data for this Ligand-Target Pair
Affinity DataEC50: 134nMAssay Description:Agonist activity at rat M3'(3C)-Xa receptor K93C/R551C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h...More data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Agonist activity at rat M3'(3C)-Xa receptor V94C/T549C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Agonist activity at rat M3'(3C)-Xa receptor V94C/F550C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h...More data for this Ligand-Target Pair
Affinity DataEC50: 423nMAssay Description:Agonist activity at rat M3'(3C)-Xa receptor N95C/T549C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h...More data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Agonist activity at rat M3'(3C)-Xa receptor N95C/F550C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h...More data for this Ligand-Target Pair
Affinity DataEC50: 1.21E+4nMAssay Description:Agonist activity at rat M3'(3C)-Xa receptor N95C/R551C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h...More data for this Ligand-Target Pair
Affinity DataEC50: 90nMAssay Description:Agonist activity at rat M3'(3C)-Xa receptor F92C/R551C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h...More data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Agonist activity at rat M3'(3C)-Xa receptor A91C/T549C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h...More data for this Ligand-Target Pair
Affinity DataEC50: 4.30nMAssay Description:Agonist activity at rat M3'(3C)-Xa receptor F92C/F550C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h...More data for this Ligand-Target Pair
Affinity DataEC50: 67nMAssay Description:Agonist activity at rat M3'(3C)-Xa receptor V94C/K548C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h...More data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Agonist activity at rat M3'(3C)-Xa receptor F92C/T549C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h...More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Agonist activity at rat M3'(3C)-Xa receptor V94C/R551C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h...More data for this Ligand-Target Pair
Affinity DataEC50: 148nMAssay Description:Agonist activity at rat M3'(3C)-Xa receptor N95C/K548C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h...More data for this Ligand-Target Pair
Affinity DataEC50: 38nMAssay Description:Agonist activity at rat M3'(3C)-Xa receptor A91C/K548C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
University of Arkansas
Curated by PDSP Ki Database
University of Arkansas
Curated by PDSP Ki Database
Affinity DataEC50: 25nMAssay Description:Agonist activity at human muscarinic M3 receptor expressed in HEK293 cells assessed as increase in IP1 accumulation incubated for 90 min by TR-HTRF a...More data for this Ligand-Target Pair
