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Found 3 Enz. Inhib. hit(s) with Target = 'Myeloperoxidase' and Ligand = 'BDBM357634'
TargetMyeloperoxidase(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357634(7-(naphthalen- 2-ylmethyl)- 3H-[1,2,3] triazolo[4,...)
Affinity DataIC50:  57nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins in presence of 240 mM NaCl and 10 uM H2O2 by aminophenyl fluorescein based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357634(7-(naphthalen- 2-ylmethyl)- 3H-[1,2,3] triazolo[4,...)
Affinity DataIC50:  188nMAssay Description:Inhibition of recombinant human MPO incubated for 10 mins by amplex red dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM357634(7-(naphthalen- 2-ylmethyl)- 3H-[1,2,3] triazolo[4,...)
Affinity DataIC50:  500nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog # A12222) which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent