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Found 2 Enz. Inhib. hit(s) with Target = 'Myeloperoxidase' and Ligand = 'BDBM357642'
TargetMyeloperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM357642(7-((3'-fluoro- [1,1'- biphenyl]-3- yl) methyl)- 3H...)
Affinity DataIC50:  55nMAssay Description:MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen catal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMyeloperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM357642(7-((3'-fluoro- [1,1'- biphenyl]-3- yl) methyl)- 3H...)
Affinity DataIC50:  500nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen catalog # A12222) which...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent