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Found 1 Enz. Inhib. hit(s) with Target = 'NACHT, LRR and PYD domains-containing protein 3' and Ligand = 'BDBM21613'
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM21613(2-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enamido]benz...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed C57BL/6 mouse bone marrow derived macrophages incubated for 30 mins in presence of ATP by i...More data for this Ligand-Target Pair
In DepthDetails PubMed