Found 2 Enz. Inhib. hit(s) with Target = 'NACHT, LRR and PYD domains-containing protein 3' and Ligand = 'BDBM50276380' TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
The Noguchi Institute
Curated by ChEMBL
The Noguchi Institute
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of nigericin-induced NLRP3 inflammasome activation in C57BL/6 mouse bone marrow derived macrophages assessed as reduction in LPS-stimulate...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The Noguchi Institute
Curated by ChEMBL
The Noguchi Institute
Curated by ChEMBL
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of nigericin-induced NLRP3 inflammasome activation in PMA-differentiated human THP1 cells assessed as reduction in LPS-stimulated IL-1beta...More data for this Ligand-Target Pair
