Found 7 Enz. Inhib. hit(s) with Target = 'NAD(P)H dehydrogenase [quinone] 1' and Ligand = 'BDBM35525' TargetNAD(P)H dehydrogenase [quinone] 1(Rattus norvegicus)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Competitive binding affinity to rat liver NQO1 in presence of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant human NQO1 assessed as reduction in oxidation of NADPH to NADP+ using b-lap as substrate and NADPH in presence of 0.14% (w/...More data for this Ligand-Target Pair
Affinity DataIC50: 404nMpH: 7.5 T: 2°CAssay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant NQO1 in presence of BSAMore data for this Ligand-Target Pair
