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Found 3 Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-1' and Ligand = 'BDBM2582'
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM2582(3,4-bis(1H-indol-3-yl)-1-methyl-2,5-dihydro-1H-pyr...)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of human SIRT1 by radioactive deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM2582(3,4-bis(1H-indol-3-yl)-1-methyl-2,5-dihydro-1H-pyr...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human SIRT1 by fluorescent deacetylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM2582(3,4-bis(1H-indol-3-yl)-1-methyl-2,5-dihydro-1H-pyr...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human SIRT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed