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Found 3 Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-2' and Ligand = 'BDBM50576689'
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
The University Of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50576689(CHEMBL4872893)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of human recombinant SIRT2 assessed as inhibition of substrate deacetylation using Gln-Pro-Lys-Lys- (epsilon acetyl) AMC peptide as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
The University Of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50576689(CHEMBL4872893)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of human recombinant SIRT2 assessed as inhibition of substrate deacetylation using Gln-Pro-Lys-Lys- (epsilon acetyl) AMC peptide as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
The University Of Hong Kong

Curated by ChEMBL
LigandPNGBDBM50576689(CHEMBL4872893)
Affinity DataKd:  4.40E+4nMAssay Description:Binding affinity to chip-immobilized recombinant human SIRT2 measured after 300 secs by surface plasmon resonance methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed