Found 3 Enz. Inhib. hit(s) with Target = 'Na(+)/H(+) exchange regulatory cofactor NHE-RF1' and Ligand = 'BDBM50509994'
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of NHERF1 in human SW620 cells expressing NHERF1 assessed as inhibition cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair