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Found 3 Enz. Inhib. hit(s) with Target = 'Na(+)/H(+) exchange regulatory cofactor NHE-RF1' and Ligand = 'BDBM50509994'
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50509994(CHEMBL4449346)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50509994(CHEMBL4449346)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of NHERF1 in human SW620 cells expressing NHERF1 assessed as inhibition cell growth incubated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNa(+)/H(+) exchange regulatory cofactor NHE-RF1(Homo sapiens)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50509994(CHEMBL4449346)
Affinity DataIC50:  8.40E+4nMAssay Description:Inhibition of NHERF1 in human Ls174T cells stably transfected with Dox-inducible shRNA for beta-catenin (Ls174Tsh-beta-Cat) assessed as inhibition of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed