Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Neprilysin/Angiotensin-converting enzyme' and Ligand = 'BDBM298325'
TargetNeprilysin/Angiotensin-converting enzyme(Homo sapiens (Human))
Theravance Biopharma R&D Ip

US Patent
LigandPNGBDBM298325((2R,4S)-5-Biphenyl-4-yl-2-hydroxy-5-methyl-4-(oxal...)
Affinity DataKi:  35.5nMAssay Description:The assays were performed in 384-well white opaque plates at 37? C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetNeprilysin/Angiotensin-converting enzyme(Homo sapiens (Human))
Theravance Biopharma R&D Ip

US Patent
LigandPNGBDBM298325((2R,4S)-5-Biphenyl-4-yl-2-hydroxy-5-methyl-4-(oxal...)
Affinity DataKi:  55nMAssay Description:Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent