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Found 3 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-3/beta-4' and Ligand = 'BDBM50246826'
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50246826(CHEMBL4084577)
Affinity DataKi:  1.03E+3nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK cell membranes after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50246826(CHEMBL4084577)
Affinity DataIC50:  6.73E+3nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in HEK cells assessed as inhibition of Ca2+ fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50246826(CHEMBL4084577)
Affinity DataEC50:  3.51E+3nMAssay Description:Agonist activity at rat alpha3beta4 nAChR expressed in HEK cells assessed as induction of Ca2+ fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed