Found 3 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-4/beta-2' and Ligand = 'BDBM50465457' TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Indiana State University
Curated by ChEMBL
Indiana State University
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR (unknown origin) expressed in HEK cell membranes after 4 hrs by liquid scintillation counting ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Indiana State University
Curated by ChEMBL
Indiana State University
Curated by ChEMBL
Affinity DataEC50: 45nMAssay Description:Agonist activity at rat alpha4beta2 expressed in Xenopus oocytes at -60 mV holding potential by electrophysiology methodMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Indiana State University
Curated by ChEMBL
Indiana State University
Curated by ChEMBL
Affinity DataEC50: 5.60E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR by cell-based rubidium flux assayMore data for this Ligand-Target Pair
