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Found 4 Enz. Inhib. hit(s) with Target = 'Neuropeptide FF receptor 2' and Ligand = 'BDBM50037573'
TargetNeuropeptide FF receptor 2(RAT)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037573((S)-2-[((S)-Pyrrolidine-2-carbonyl)-amino]-pentane...)
Affinity DataKi:  15.5nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50037573((S)-2-[((S)-Pyrrolidine-2-carbonyl)-amino]-pentane...)
Affinity DataKi:  25nMAssay Description:Displacement of [125I]-1DMeNPFF from human NPFFR2 expressed in HEK293 cells incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(RAT)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50037573((S)-2-[((S)-Pyrrolidine-2-carbonyl)-amino]-pentane...)
Affinity DataKi:  25nMAssay Description:Displacement of [125I]-1DMeNPFF from rat NPFFR2 expressed in HEK293 cells incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide FF receptor 2(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50037573((S)-2-[((S)-Pyrrolidine-2-carbonyl)-amino]-pentane...)
Affinity DataEC50:  309nMAssay Description:Agonist activity at human NPFFR2 expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cyclic cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed