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Found 11 Enz. Inhib. hit(s) with Target = 'Neuropeptide Y receptor type 2' and Ligand = 'BDBM50197025'
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197025(CHEMBL439904 | PYY(3-36))
Affinity DataKi:  0.400nMAssay Description:Displacement of human [125I]PYY from NPY2 receptor expressed in human KAN-TS cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197025(CHEMBL439904 | PYY(3-36))
Affinity DataIC50:  0.570nMAssay Description:Displacement of [125I]peptide YY from human Y2 receptor expressed in CHO cell membranes after 60 mins by TopCount scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197025(CHEMBL439904 | PYY(3-36))
Affinity DataIC50:  0.570nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197025(CHEMBL439904 | PYY(3-36))
Affinity DataIC50:  16nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197025(CHEMBL439904 | PYY(3-36))
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells co-transfected with CRE-luciferase incubated for 24 hrs in presence of 10% FBS by One-Glo l...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197025(CHEMBL439904 | PYY(3-36))
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human NPY2R expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation incubated for 30 m...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197025(CHEMBL439904 | PYY(3-36))
Affinity DataEC50:  1nMAssay Description:Agonist activity at human NPY2R expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation incubated for 30 m...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197025(CHEMBL439904 | PYY(3-36))
Affinity DataEC50:  0.280nMAssay Description:Agonist activity at human Y2 receptor expressed in CHO cell membranes after 120 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197025(CHEMBL439904 | PYY(3-36))
Affinity DataEC50:  1nMAssay Description:Agonist activity at human NPYY2 receptor expressed in HEK293 cells assessed as decrease in isoproterenol-induced cAMP level measured every 30 secs fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197025(CHEMBL439904 | PYY(3-36))
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human NPY2 receptor expressed in human KAN-TS cells by [35S]GTPgammaS incorporation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50197025(CHEMBL439904 | PYY(3-36))
Affinity DataEC50:  0.280nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed