Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Neutrophil collagenase' and Ligand = 'BDBM389618'
TargetNeutrophil collagenase(Homo sapiens (Human))
University of Notre Dame Du Lac

US Patent
LigandPNGBDBM389618(US10357546, ND-336 | US9951035, ND-336 (5))
Affinity DataKi:  150nMAssay Description:Human recombinant active MMP-2 and MMP-7, and the catalytic domains of MMP-3 and MMP-14/MT1-MMP were purchased from EMD Chemicals, Inc. (San Diego, C...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil collagenase(Homo sapiens (Human))
University of Notre Dame Du Lac

US Patent
LigandPNGBDBM389618(US10357546, ND-336 | US9951035, ND-336 (5))
Affinity DataKi:  7.70E+3nMAssay Description:Inhibition of MMP8 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University of Notre Dame Du Lac

US Patent
LigandPNGBDBM389618(US10357546, ND-336 | US9951035, ND-336 (5))
Affinity DataKi:  7.70E+3nMAssay Description:Non-competitive inhibition of human recombinant MMP8 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University of Notre Dame Du Lac

US Patent
LigandPNGBDBM389618(US10357546, ND-336 | US9951035, ND-336 (5))
Affinity DataKi:  7.70E+3nMAssay Description:The term selective inhibitor as used in reference to MMPs refers to an inhibitor that inhibits the enzymatic activity of one MMP in the presence of o...More data for this Ligand-Target Pair
In DepthDetails US Patent