Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with Target = 'Neutrophil elastase' and Ligand = 'BDBM50032888'
TargetNeutrophil elastase(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50032888(CHEMBL3342778 | US9290459, 6.3 | US9670166, 6.3)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-Ala-Ala-Pro-Val-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50032888(CHEMBL3342778 | US9290459, 6.3 | US9670166, 6.3)
Affinity DataIC50:  3.70nMpH: 7.5 T: 2°CAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50032888(CHEMBL3342778 | US9290459, 6.3 | US9670166, 6.3)
Affinity DataIC50:  3.70nMpH: 7.5 T: 2°CAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50032888(CHEMBL3342778 | US9290459, 6.3 | US9670166, 6.3)
Affinity DataEC50:  4nMAssay Description:Inhibition of neutrophil elastase in human plasma using MeOSuc-Ala-Ala-Pro-Val-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50032888(CHEMBL3342778 | US9290459, 6.3 | US9670166, 6.3)
Affinity DataEC50:  4nMpH: 7.5Assay Description:Various concentrations of the neutrophil elastase inhibitor are incubated with plasma. Subsequently, the enzyme activity is measured using the fluoro...More data for this Ligand-Target Pair
In DepthDetails US Patent