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Found 5 Enz. Inhib. hit(s) with Target = 'Nicotinamide N-methyltransferase' and Ligand = 'BDBM50247634'
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Biokin

Curated by ChEMBL
LigandPNGBDBM50247634(CHEMBL4067973)
Affinity DataKi:  89nMAssay Description:Inhibition of N-terminal His6-tagged wild type human NNMT expressed in Escherichia coli NiCo21(DE3) assessed as reduction in 1-methylquinolinium leve...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Biokin

Curated by ChEMBL
LigandPNGBDBM50247634(CHEMBL4067973)
Affinity DataKi:  89nMAssay Description:Inhibition of N-terminal His6-tagged wild type human NNMT expressed in Escherichia coli NiCo21(DE3) assessed as reduction in 1-methylquinolinium leve...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Biokin

Curated by ChEMBL
LigandPNGBDBM50247634(CHEMBL4067973)
Affinity DataIC50:  4.36E+3nMAssay Description:Inhibition of wild-type human full length NNMT expressed in Escherichia coli BL21(DE3) cells assessed as reduction in 1-methyl-nicotinamide formation...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Biokin

Curated by ChEMBL
LigandPNGBDBM50247634(CHEMBL4067973)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human NNMT (1 to 264 residues) expressed in Escherichia coli BL21 (DE3) using nicotinamide/SAM as substrate/co-factor measured for 20 m...More data for this Ligand-Target Pair
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Biokin

Curated by ChEMBL
LigandPNGBDBM50247634(CHEMBL4067973)
Affinity DataKd:  2.70E+3nMAssay Description:Binding affinity to human NNMT (1 to 264 residues) expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetric methodMore data for this Ligand-Target Pair