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Found 5 Enz. Inhib. hit(s) with Target = 'Nicotinamide N-methyltransferase' and Ligand = 'BDBM50247635'
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Biokin

Curated by ChEMBL
LigandPNGBDBM50247635(CHEMBL4100002)
Affinity DataKi:  912nMAssay Description:Inhibition of N-terminal His6-tagged wild type human NNMT expressed in Escherichia coli NiCo21(DE3) assessed as reduction in 1-methylquinolinium leve...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Biokin

Curated by ChEMBL
LigandPNGBDBM50247635(CHEMBL4100002)
Affinity DataKi:  912nMAssay Description:Inhibition of N-terminal His6-tagged wild type human NNMT expressed in Escherichia coli NiCo21(DE3) assessed as reduction in 1-methylquinolinium leve...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Biokin

Curated by ChEMBL
LigandPNGBDBM50247635(CHEMBL4100002)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Biokin

Curated by ChEMBL
LigandPNGBDBM50247635(CHEMBL4100002)
Affinity DataIC50:  1.60E+5nMAssay Description:Inhibition of human NNMT (1 to 264 residues) expressed in Escherichia coli BL21 (DE3) using nicotinamide/SAM as substrate/co-factor measured for 20 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Biokin

Curated by ChEMBL
LigandPNGBDBM50247635(CHEMBL4100002)
Affinity DataKd:  4.28E+4nMAssay Description:Binding affinity to human NNMT (1 to 264 residues) expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed