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Found 2 Enz. Inhib. hit(s) with Target = 'Nicotinamide phosphoribosyltransferase' and Ligand = 'BDBM455792'
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM455792(N-[[6-(2,2- dimethylcyclopropanecarbonyl)- 6-azasp...)
Affinity DataIC50:  14.9nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Valo Health

US Patent
LigandPNGBDBM455792(N-[[6-(2,2- dimethylcyclopropanecarbonyl)- 6-azasp...)
Affinity DataIC50:  21.6nMAssay Description:NAMPT Protein Purification. Recombinant His-tagged NAMPT was produced in E. coli cells, purified over a Ni column, and further purified over a size-e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent