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Found 10 Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, brain' and Ligand = 'BDBM50209245'
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
North-West University

Curated by ChEMBL
LigandPNGBDBM50209245(CHEMBL247378)
Affinity DataIC50:  110nMAssay Description:Inhibition of nNOS in Sprague-Dawley rat brain homogenates assessed as conversion of oxyhemoglobin to methemoglobin measured for 10 mins by UV-visibl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
North-West University

Curated by ChEMBL
LigandPNGBDBM50209245(CHEMBL247378)
Affinity DataIC50:  600nMAssay Description:Inhibition of rat neuronal NOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Uned

Curated by ChEMBL
LigandPNGBDBM50209245(CHEMBL247378)
Affinity DataIC50:  710nMAssay Description:Inhibition of NOS1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
North-West University

Curated by ChEMBL
LigandPNGBDBM50209245(CHEMBL247378)
Affinity DataIC50:  800nMAssay Description:In vitro inhibitory concentration against rat cerebellar neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
North-West University

Curated by ChEMBL
LigandPNGBDBM50209245(CHEMBL247378)
Affinity DataIC50:  2.00E+3nMAssay Description:Tested to inhibit the conversion of [3H]-L-arginine to [3H]-L-citrulline catalyzed by neuronal NOS from rat cerebellum.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
North-West University

Curated by ChEMBL
LigandPNGBDBM50209245(CHEMBL247378)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibitory activity against rat neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Uned

Curated by ChEMBL
LigandPNGBDBM50209245(CHEMBL247378)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Uned

Curated by ChEMBL
LigandPNGBDBM50209245(CHEMBL247378)
Affinity DataIC50:  2.87E+3nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
North-West University

Curated by ChEMBL
LigandPNGBDBM50209245(CHEMBL247378)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of rat brain recombinant nNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
North-West University

Curated by ChEMBL
LigandPNGBDBM50209245(CHEMBL247378)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of rat recombinant nNOS expressed in Saccharomyces cerevisiae assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed