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Found 3 Enz. Inhib. hit(s) with Target = 'Nitric oxide synthase, inducible' and Ligand = 'BDBM50111438'
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50111438(3-{[(Benzo[1,3]dioxol-5-ylmethyl)-carbamoyl]-methy...)
Affinity DataKi:  2.20nMAssay Description:Binding against the partially purified human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50111438(3-{[(Benzo[1,3]dioxol-5-ylmethyl)-carbamoyl]-methy...)
Affinity DataIC50:  0.380nMAssay Description:Inhibition of cytokine-induced iNOS expressed in human A172 cells assessed as inhibition of NO formationMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50111438(3-{[(Benzo[1,3]dioxol-5-ylmethyl)-carbamoyl]-methy...)
Affinity DataIC50:  0.600nMAssay Description:Inhibitory activity against the partially purified human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair