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Found 4 Enz. Inhib. hit(s) with Target = 'Non-lysosomal glucosylceramidase' and Ligand = 'BDBM50312527'
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312527(CHEMBL1086996 | N-[5-(Adamantan-1-yl-methoxy)-pent...)
Affinity DataIC50: <1nMAssay Description:Inhibition of GBA2 by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312527(CHEMBL1086996 | N-[5-(Adamantan-1-yl-methoxy)-pent...)
Affinity DataIC50:  1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312527(CHEMBL1086996 | N-[5-(Adamantan-1-yl-methoxy)-pent...)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant GBA2 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50312527(CHEMBL1086996 | N-[5-(Adamantan-1-yl-methoxy)-pent...)
Affinity DataIC50:  30nMAssay Description:Inhibition of glucosylceramidase 2 from spleen of patient with gaucher's disease by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed