BindingDB PrimarySearch

Found 1 Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK1/Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50585519'

Non-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK1/Tyrosine-protein kinase JAK2(Homo sapiens (Human))
Gsk

Curated by ChEMBL

BDBM50585519(CHEMBL5075556)

IC50: 20nMAssay Description:Inhibition of JAK1/JAK2/TYK1 in human lung fibroblast cells assessed as IL-13 induced eotaxin production incubated for 20 to 24 hrs by MSD assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
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3D Structure (crystal)