Found 1 Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50545650' TargetNon-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK2(Homo sapiens (Human))
Japan Tobacco
Curated by ChEMBL
Japan Tobacco
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of JAK2/Tyk2 in human PBMC assessed as reduction in IL-23-induced Stat3 phosphorylation in CD3+CD4+ cells preincubated for 30 mins followe...More data for this Ligand-Target Pair
