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Found 6 Enz. Inhib. hit(s) with Target = 'Nonstructural protein 5A' and Ligand = 'BDBM244106'
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM244106(US9428491, 1.1 | US9428491, 1.1: 2HCl | US9428491,...)
Affinity DataIC50:  0.00500nMAssay Description:Inhibition of HCV genotype 1b NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by Celltiter Glo a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM244106(US9428491, 1.1 | US9428491, 1.1: 2HCl | US9428491,...)
Affinity DataIC50:  0.0280nMAssay Description:Inhibition of HCV genotype 4a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM244106(US9428491, 1.1 | US9428491, 1.1: 2HCl | US9428491,...)
Affinity DataIC50:  0.0840nMAssay Description:Inhibition of HCV genotype 2a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM244106(US9428491, 1.1 | US9428491, 1.1: 2HCl | US9428491,...)
Affinity DataIC50:  0.215nMAssay Description:Inhibition of HCV genotype 1a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM244106(US9428491, 1.1 | US9428491, 1.1: 2HCl | US9428491,...)
Affinity DataIC50:  0.407nMAssay Description:Inhibition of HCV genotype 5a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM244106(US9428491, 1.1 | US9428491, 1.1: 2HCl | US9428491,...)
Affinity DataIC50:  2.45nMAssay Description:Inhibition of HCV genotype 3a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed