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Found 2 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM475882'
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM475882(2-(4-((3-(2,6-dichloro-2′-(trifluoromethoxy)...)
Affinity DataIC50:  124nMAssay Description:Inverse agonist activity at human RORgammat assessed as inhibition of N-terminal biotinylated co-activator SRC1 recruitment measured after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM475882(2-(4-((3-(2,6-dichloro-2′-(trifluoromethoxy)...)
Affinity DataIC50: <500nMAssay Description:The inhibitory activity of compounds on RORγ receptor was determined by fluorescence resonance energy transfer (FRET) experiments. The inhibitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent