Affinity DataIC50: 10nMpH: 7.4Assay Description:On day of the assay, 100 uL of 0.05% CHAPS (in deionized H2O) was added
to all wells of the GFB Unifilter plate and allowed soak for 1 h. A wash
bu...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [3H2]-25-hydroxycholesterol from N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial express...More data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Inverse agonist activity at GAL4-fused human RORc expressed in HEK293T cells assessed as suppression of basal transcriptional activity after 20 hrs b...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Inverse agonist activity at N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial expression system assessed a...More data for this Ligand-Target Pair