Found 4 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM50446283' 
Affinity DataIC50: 6nMAssay Description:Inverse agonist activity at biotinylated human RORgammat LBD expressed in Escherichia coli BL21 assessed as inhibition of SRC1 recruitment after 1 hr...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inverse agonist activity at RORgammat in mouse Th17 cells assessed as effect on cell differentiation measured as IL-17 level after 3 days by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: 9nMAssay Description:Activity at RoRc in mouse CD4+ T cells assessed as inhibition of IL-17 productionMore data for this Ligand-Target Pair
