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Found 3 Enz. Inhib. hit(s) with Target = 'Nuclear receptor ROR-gamma' and Ligand = 'BDBM50552535'
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50552535(CHEMBL4796044)
Affinity DataEC50:  11nMAssay Description:Agonist activity at Gal4-fused RORgammat (unknown origin) expressed in Jurkat cells by reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Mus musculus)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50552535(CHEMBL4796044)
Affinity DataEC50:  30nMAssay Description:Agonist activity at RORgammat in C57/B6 mouse Th17 cells assessed as increase in IL17A expression after 96 hrs by AlphaLISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50552535(CHEMBL4796044)
Affinity DataEC50:  45nMAssay Description:Agonist activity at RORgammat in human Whole blood assessed as increase in IL17 expression after 48 hrs by AlphaLISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB