Found 7 Enz. Inhib. hit(s) with Target = 'Nuclear receptor subfamily 5 group A member 2' and Ligand = 'BDBM50418303' TargetNuclear receptor subfamily 5 group A member 2(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 374nMAssay Description:Displacement of 6N-FAM from human LRH1 LBD (299 to 541 residues) expressed in Escherichia coli BL21 pLysS by competitive binding based fluorescence p...More data for this Ligand-Target Pair
3D Structure (crystal)TargetNuclear receptor subfamily 5 group A member 2(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Binding affinity to human LRH-1More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 5 group A member 2(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataEC50: 600nMAssay Description:Agonist activity at recombinant human LRH1 ligand binding domain (300 to 537 residues) expressed in Escherichia coli BL21 cells assessed as increase ...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 5 group A member 2(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataEC50: 1.10E+3nMAssay Description:Agonist activity at human full length LRH1 transfected in human HeLa cellsMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 5 group A member 2(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataEC50: 1.10E+3nMAssay Description:Agonist activity at recombinant full length human LRH1 expressed in HeLa cells after 24 hrs by dual-glo luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 5 group A member 2(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataEC50: 251nMAssay Description:Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to controlMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 5 group A member 2(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataEC50: 1.50E+3nMAssay Description:Agonist activity at human full length LRH1 transfected in human HeLa cells incubated for 24 hrs by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
