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Found 2 Enz. Inhib. hit(s) with Target = 'Orexin receptor type 2' and Ligand = 'BDBM50108614'
TargetOrexin receptor type 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50108614(CHEMBL3597959 | US9695163, 19)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at human orexin-2 receptor expressed in CHO cells assessed as inhibition of human orexin-A-induced Ca2+ flux preincubated for 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50108614(CHEMBL3597959 | US9695163, 19)
Affinity DataIC50:  14nMT: 2°CAssay Description:Briefly, for intracellular calcium measurements, Chinese hamster ovary (CHO) cells expressing the orexin-1 receptor (e.g., rat or human) or the orexi...More data for this Ligand-Target Pair
In DepthDetails US Patent