Affinity DataIC50: 8.70nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Antagonist activity at P2X7 receptor in human whole blood assessed as inhibition of BzATP-induced IL1beta release incubated 30 mins prior to BzATP-ch...More data for this Ligand-Target Pair