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Found 2 Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM50251605'
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50251605(4-(carbamimidoyl)-N-(4-chlorophenyl)-2-isopropylpi...)
Affinity DataIC50:  110nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor assessed as inhibition of BzATP induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50251605(4-(carbamimidoyl)-N-(4-chlorophenyl)-2-isopropylpi...)
Affinity DataIC50:  112nMAssay Description:Antagonist activity at human recombinant P2X7 receptor assessed as inhibition of BzATP induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed